Panama Cities to Visit

Sometimes it's not that you want to leave 'the city' it's that you want to leave 'your city' — explore new surroundings and treat yourself to new markets, shops, museums, restaurants, architecture, and more when you peruse this list of Panama's cities to visit. You'll get the change of pace you need, and will also enjoy easy access to the outdoor adventure the country offers.

Panama City is the most metropolitan city in all of Central America. With abundant cultural and culinary opportunities, it’s a fun place to visit. There are, however, other Panamanian cities worth noting. Chitré is a great place to explore Panama's Azuero culture, while Pedasi is a pristine town with lovely Spanish-Colonial architecture. To discover what else is waiting for you, you'll have to review this list of Panama's cities — these destinations are active, interesting, and typically have a solid offering of restaurants, bars, and cultural curiosities.

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10 Panama Cities to Visit

The places our local insiders recommend most come first.

Panama City

Panama City is a hub in every sense of the word. Located in the Gulf of Panama along the Pacific Coast, Panama City sits in the heart of the country and serves as the main artery through which the rest of Panama receives its visitors, commerce, and culture.

Panama City

Destination

Bocas Town

Bocas town is a bohemian, waterfront town on Isla Colón. It's the largest and funkiest town in the Bocas del Toro archipelago and is visited by travelers from all over the world. Hotels, restaurants, gourmet grocery stores and other tourist facilities crowd the small town, making it one of the most popular places in all of Panama.

Bocas Town

Destination

Pedasi

The tiny town of Pedasí is slowly emerging as one of Panama’s up-and-coming tourist destinations. Located in the southeastern corner of the Azuero Peninsula, it is tidy, charming, and friendly. The buildings are decorated with some wonderfully intact Spanish-colonial architecture, and there are a number of pristine beaches close to town. Visitors to Pedasí can take trips to the wildlife sanctuary of Isla Iguana, which lays just off the coast, or head down the Azuero 34 km to the surf-haven of Playa Venao.

Pedasi

Destination

David

David, the provincial capital of Chiriquí province, is the second largest city in Panama (pop. 140,000) and the hub for visits to the highlands or other parts of western Panama. Though there are attractive areas within the city, David primarily serves as a place to refuel before launching into other adventures within the region.

David

Destination

Chitré

Chitré, capital of the Herrera province, is the largest city on the Azuero Peninsula. For most, Chitré serves as a convenient place to refuel or transfer buses before heading down the peninsula, as there is an ample amount of stores, restaurants, and accommodations in town. However, Chitré also has a vibrant Azuero culture and a history of its own, with a sprinkling of places that visitors will find attractive.

Chitré

Destination

Las Tablas

For all but a week of the year, Las Tablas (pop. 7,980) is a mellow and conventional Azuero Peninsula town, noted mostly for its close proximity to Chitré and Pedasí. However, Las Tablas is turned upside down in an all-out, booze-soaked party during the annual celebration of Carnaval.

Las Tablas

Destination

Santiago

Santiago is the provincial capital of Veraguas and one of Panama’s largest cities. It sits along the Inter-American Highway midway between David and Panama City, and acts as an important transportation hub for central Panama. There is little within the city that will interest most visitors, but there are a wide range of services and amenities available. Because of its central location and excellent facilities, Santiago serves as a good stopover while en route to other destinations.

Santiago

Destination

La Palma

La Palma is the provincial capital of the Darién Province. It’s a small town, with fewer than 4,000 residents. Most travelers only stop here while en route to other destinations in the Darién.

La Palma

Destination

Parita

Parita is a cute and tidy town6 miles (10 km) northwest of Chitré. Its Spanish colonial roots are easy to see while walking around, particularly in the town’s church and other buildings. It is a nice place to stroll and take pictures.

Parita

Destination

Colon

Colón, which lies along the central Caribbean coast of Panama, has historically been the country’s second-most important city. Today, however, Colón is riddled with poverty and crime. Aside from large corporate purchases at Zona Libre de Colón (Colón’s Free Trade Zone), most tourists these days are advised to stay away from the city.

Colon

Destination

Trips to Inspire

Panama Cities to Visit itineraries from local insiders

Explore hand-picked Panama Cities to Visit itineraries designed by local insiders who know every hidden corner. Each trip is completely flexible, customized to your pace, travel style, and budget.

9 daysFrom $1,090 per person

A Beautiful Vacation Beyond Our Expectations

It was a beautiful vacation.

A Beautiful Vacation Beyond Our Expectations

Panama

8 daysFrom $2,198 per person

A Spring Surf and Sun Getaway

Beautiful place. Everyone we interacted with was so helpful, kind, and patient. They made us feel at home.

A Spring Surf and Sun Getaway

Panama

13 daysInquire

A Birding Journey in The Tropics

Grab your binoculars and your guidebook! You're about to check a variety of beautiful birds off of your list in the rainforests and cloud forests of Panama.

A Birding Journey in The Tropics

Panama

9 daysFrom $928 per person

Canal, Beach, & Nature = Family Fun

This vacation, do a little of everything when you explore the city, forest, and beach on this awesome family getaway to Panama. Nature and knowledge await you.

Canal, Beach, & Nature = Family Fun

Panama

9 daysInquire

Coming Solo, Leaving with Memories

Walk through local markets; go on long hikes; soak in a hot spring; this is your vacation, your way. Explore Panama at your own pace with this spectacular getaway for one.

Coming Solo, Leaving with Memories

Panama

8 daysInquire

A 'Friend-Ship' Sails to Panama

From wild nights in Panama city to beaches and brews in Bocas del Toro, awesome adventures and amazing memories are waiting for you and your friends in Panama.

A 'Friend-Ship' Sails to Panama

Panama

9 daysInquire

Exploring Panama at The Pace of You

Take yourself on a grand getaway in paradise full of Caribbean cuisine, cultural exchanges, and exciting adventures. It’s as simple as booking this Signature Trip to Panama.

Exploring Panama at The Pace of You

Panama

9 daysFrom $790 per person

A 'Best Of' Panama Family Adventure

This family adventure is a trip to paradise complete with magical forests, stunning beaches, marine wildlife, vibrant cities, and memories waiting to be made. Welcome to Panama.

A 'Best Of' Panama Family Adventure

Panama

8 daysInquire

Exploring Panama Together

This vacation, learn about the vibrant country of Panama as you explore its cities, forests, and even island beaches first hand. Go somewhere new –– together.

Exploring Panama Together

Panama

9 daysInquire

Panama: A Soulmate's Journey

Reconnect with the person you love the most when you go on an amazing adventure –– from cosmopolitan cities, to cloud forests, and an island beach, see all of Panama.

Panama: A Soulmate's Journey

Panama

Belong Anywhere

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