Cruise the Mekong River from Siem Reap Cambodia to Saigon Vietnam
This itinerary is the starting point for a great trip to Vietnam & Cambodia. All services can be customized to suit your travel needs, dates, and budget. You may be looking for hotels or other options, such as alternative lodging. Our local experts will help you in Southeast Asia. Get in touch to plan your trip to Vietnam, Cambodia and other Southeast Asian countries.
Places you'll stay
Siem Reap
The ancient stone silhouettes of Angkor rise just a short drive from Siem Reap, making the city the primary gateway for visitors eager to explore the Khmer Empire’s temple complex. Siem Reap sits in northwestern Cambodia as the capital of its namesake province and serves as the country’s second‑largest urban centre. Its reputation as a tourism hub grew after the city was named the ASEAN City of Culture for 2021–2022 at a regional ministers’ meeting in October 2020.
Destination
Ho Chi Minh City
There’s no better place to get a feel for urban Vietnam than the energetic streets of Ho Chi Minh City. This is Vietnam's largest city and one of the country's most free-spirited destinations. Still referred to as ‘Saigon’ by locals, it is known for hordes of motorbikes, mouthwatering food, and hip coffee shops.
Destination
Moments to look forward to
Cu Chi Tunnels
Drive a little ways outside of Ho Chi Minh City to discover what remains of the Cu Chi Tunnels. These tunnels were crucial to the North Vietnamese resistance.
Attraction
Angkor Wat
Covering 162.6 hectares, the temple complex at Angkor Wat holds the record as the world’s largest religious structure. Built between 1113 and 1150 CE in the ancient capital of Angkor, it now functions as a Theravada Buddhist site in Siem Reap, Cambodia, while its silhouette appears on the national flag.
Attraction
Mekong Delta Cruise
A wooden sampan glides past rows of banana trees, then slows beside a floating market where vendors shout in Khmer while balancing baskets of fish on their heads. The Mekong Delta Cruise in Cambodia follows the lower Mekong from Phnom Penh toward the Tonle Sap confluence, offering a close‑up view of river life that rarely appears in guidebooks. It is a multi‑day journey that combines transport, accommodation and guided interpretation on a single vessel, and it operates entirely within Cambodian borders.
Attraction
Siem Reap
Angkor Archaeological Park
Tour
Siem Reap
From Siem Reap to Kampong Cham to Check in Cruise
Tour
Mekong Delta Cruise
Discover Angkor Ban Charming Town
Tour
Mekong Delta Cruise
Discover the Historic Site in Phnom Penh
Tour
Mekong Delta Cruise
Cross the Border into Vietnam
Tour
Mekong Delta Cruise
Hoa An Village, Cruise to Can Tho
Tour
Mekong Delta Cruise
Cai Rang Floating Market Experience
Tour
Mekong Delta Cruise
Explore Ben Tre on Sampan. Arrive Ho Chi Minh City
Tour
Mekong Delta Cruise
Visit Cu Chi Tunnel and Highlight Sightseeing
Tour
Incredible Stays
Hotel Recommendation #1
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Hotel Recommendation #2
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Hotel Recommendation #3
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Curated to you
Insider-led Vietnam Design & Concierge
Your insider team designs the trip around what you care about, then supports you in-country with private logistics, vetted partners, and concierge help when plans change.
