No vaccinations are officially required to enter Guatemala. That said, it’s a good idea to be up-to-date on typhoid, rabies, yellow fever, measles-mumps-rubella (MMR), and tetanus shots. Getting the hepatitis vaccine also makes sense. If you’ll be visiting rural lowland areas you might want to take malaria pills — you’ll need to begin taking these a few weeks before being potentially exposed to the disease.
Health conditions and vaccination recommendations do change, however, so it’s best to check with your doctor for current requirements before traveling.
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